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SIRT3 regulation of mitochondrial oxidative stress

Duff BJ, Macritchie KAN, Moorhead TWJ, Lawrie SM, Blackwood DHR

This antagonistic relationship extends to mitochondrial function H 2 S scavenges ONOO , a cytotoxic reactive nitrogen species, an effect that can be mitigated by H 2 S, thereby creating a complex regulatory loop that governs mitochondrial dysfunction and redox balance (109)

10.2147/DDDT.S83144 Drug Des Devel Ther